Application of Biochemical Screening Protocols in Occupational Health Management in the Nigerian Oil Industry

Occupational exposure to petrochemical substances in Nigeria's oil and gas sector poses significant risks to worker health, necessitating robust biochemical screening frameworks. This study examines the application of biochemical screening protocols for liver function, renal function, and haematological indices in workers at a refinery in Rivers State, South South Nigeria. A cross-sectional occupational health audit design was employed, involving 200 workers drawn from various exposure categories including processing plant operators, laboratory technicians, and administrative staff. Liver function tests, full blood count, serum creatinine, urea, and urine analysis were conducted as part of a structured periodic medical examination. The study evaluates whether current occupational health protocols are sufficient to detect early biochemical signs of petrochemical toxicity and proposes enhancements aligned with current international occupational medicine guidelines. Duration of employment, use of personal protective equipment, and shift patterns were documented as modifying variables. The study also assesses compliance with existing regulatory requirements from the Nigerian National Petroleum Corporation. Comparative analysis across departments will identify the occupational categories with the greatest biochemical risk burden. Recommendations for a standardised, evidence-based biochemical surveillance programme for the Nigerian oil industry are proposed. Keywords: occupational biochemistry, petrochemical toxicity, liver function, oil industry, Rivers State.