Prevalence of Sickle Cell Anaemia Complications Among Adolescents at Paediatric Haematology Clinic, University College Hospital, Ibadan

Sickle cell anaemia is among the most prevalent inherited haematological disorders in Nigeria, and the adolescent period presents unique challenges for disease management as patients transition from paediatric to adult care. This study examines the prevalence and types of acute and chronic complications among adolescents with sickle cell anaemia aged 10 to 19 years attending the paediatric haematology clinic at University College Hospital, Ibadan, Oyo State. A retrospective cross-sectional design is applied to case records over a three-year period from 2020 to 2022. Data include genotype (HbSS, HbSC), hydroxyurea use, number and type of vaso-occlusive crises, acute chest syndrome episodes, stroke history, avascular necrosis, priapism, retinal complications, and transcranial Doppler screening results. SPSS is used for analysis. Available paediatric haematology literature from UCH Ibadan identifies vaso-occlusive crisis as the most frequent acute complication, with avascular necrosis and stroke-related disability among the most clinically impactful chronic sequelae in adolescents. The NHLBI Evidence-Based Management Guidelines for Sickle Cell Disease provide the clinical management framework. Findings will support the clinic in developing a structured transition programme for adolescents moving to adult haematology services. Keywords: sickle cell anaemia, adolescents, complications, University College Hospital, South West Nigeria.