📖 ABSTRACT/OVERVIEW
Background: Coronary artery disease (CAD) is an increasingly prevalent cardiovascular condition in Nigeria, requiring lifelong polypharmacy for secondary prevention. Poor medication adherence in CAD patients significantly increases the risk of recurrent events and mortality. This study examined socioeconomic and behavioural predictors of medication adherence among CAD patients in Lagos State. Methods: A prospective analytical study enrolled 280 CAD patients from cardiology outpatient clinics at Lagos University Teaching Hospital and Lagos Island General Hospital. Medication adherence was assessed using the MMAS-8. Structured questionnaires evaluated socioeconomic variables (income, education, employment), health beliefs (using Health Belief Model constructs), medication burden, and perceived healthcare provider support. Results: High adherence was observed in 41 percent of participants. In multivariate analysis, significant predictors of non-adherence included monthly household income below minimum wage (OR 3.1), polypharmacy of seven or more drugs (OR 2.4), low perceived disease severity (OR 1.9), and weak patient-provider relationship scores (OR 1.7). Female patients had significantly higher adherence rates than males (p less than 0.05). Conclusion: Medication adherence in CAD patients in Lagos is shaped by intersecting socioeconomic and behavioural factors. Targeted adherence support programmes addressing financial barriers and health literacy are required. Keywords: medication adherence, coronary artery disease, Lagos, polypharmacy, health belief model
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