Health-Related Quality of Life and Its Determinants in Patients with Obsessive-Compulsive Disorder at Neuropsychiatric Hospital, Aro

Obsessive-compulsive disorder (OCD) substantially impairs health-related quality of life (HRQoL), yet this relationship has not been adequately characterized in Nigerian psychiatric populations. This study examines HRQoL and its clinical and sociodemographic determinants among patients with OCD at Neuropsychiatric Hospital, Aro, Abeokuta, Ogun State, South West Nigeria. A cross-sectional design will recruit 100 patients with a confirmed OCD diagnosis through consecutive outpatient sampling. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) will assess OCD symptom severity, the WHOQOL-BREF will measure HRQoL, and the PHQ-9 will screen for comorbid depression. Predictor variables including obsession and compulsion subtypes, duration of illness, medication status, and family accommodation will be analyzed using multiple linear regression. OCD subtype, symptom severity, and comorbid depression are hypothesized to be the strongest predictors of reduced HRQoL. This study addresses a significant research gap in South West Nigeria, as OCD remains understudied relative to psychotic and mood disorders in Nigerian psychiatric institutions. Findings will support comprehensive OCD treatment planning and service development at Aro Hospital. Keywords: obsessive-compulsive disorder, quality of life, determinants, Aro Hospital, Ogun State