Urinary Protein Excretion and Kidney Function Markers in Market Women in Port Harcourt

Chronic kidney disease is frequently asymptomatic in its early stages, making community-based screening efforts critical for early identification of at-risk individuals. This study examines urinary protein excretion and selected kidney function markers, including serum creatinine, urea, and estimated glomerular filtration rate, among market women in Port Harcourt, South South Nigeria. Market women represent a population segment with high exposure to environmental nephrotoxins, limited access to healthcare, and frequent use of analgesics and herbal preparations. A cross-sectional study design was employed, recruiting 200 women aged 25 to 60 years from three major markets. Spot urine samples were analysed for protein using the sulphosalicylic acid method, and venous blood samples were processed for renal function tests. Blood pressure, body mass index, and years of market trading were also recorded. History of hypertension, diabetes, and use of non-steroidal anti-inflammatory drugs was documented by questionnaire. Results are expected to reveal a significant burden of subclinical renal impairment in this under-screened population. The study underscores the importance of integrating renal function screening into community outreach initiatives in urban South South Nigeria. Keywords: kidney function, proteinuria, chronic kidney disease, market women, Port Harcourt.